Dr. Asma Nigar, Dr. Arshiya Khan, Dr. Kusum Lata, Dr. Ausaf Ahmad


Background:  Cervical cancer ranks as the second most frequent cancer among women between 15 and 44 years of age. Cervical cancer is preventable because it has long preinvasive stage. Early cervical epithelial changes can be detected by a Pap smear test, which is the primary screening test for detection of precancerous cervical intraepithelial lesions and the early stage of invasive cervical cancer. The use of the cervical smear (Papanicolaou /Pap smear) as a screening method has significantly reduced the incidence of cervical cancer.

The aim of the present study was to evaluate the pattern of cervical cytology and its correlation with clinical findings.

Methods: It was a prospective cross sectional study  that was conducted  in 340 women  attending  Obstetrics and Gynecology  OPD  at  Integral Institute  of  Medical Sciences and Research.

This study was done over a period of 6 months. Detailed clinical data and Pap smear cytology

Reports were obtained and data was noted in a structured Proforma. All the smears were reported according to new Bethesda System for Reporting Cervical Cytology 2014. Clinical correlation with Pap smear findings was done.


Results: Among 340 screened patients (23, 6.76%) patients were found to have epithelial cell abnormality in their pap smear report.  Women in the age group of 41- 60 years showed maximum (16, 69.5 %) abnormal reports. No case of epithelial cell abnormality on pap smear was reported in women of 21-30 years of age. Maximum number (83.3 %) of ASCUS and 66.6 % of AGC were seen among women of 41-60 years of age. 3 cases of HSIL were found in 51-70 years of age.

Conclusion: In the present study, most of the abnormal epithelial reports were seen in women of age group of 41-60 years. So priority should be given to screen all women of 30 years or more with Pap smear test.


Pap test, Cervical cancer, NILM, epithelial cell abnormality.

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Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer

incidence and mortality worldwide: Sources, methods and major patterns in

GLOBOCAN 2012.Int J Cancer. 2015; 136: E359–86

ICO Information Centre on HPV and Cancer. Human Papillomavirus and Related

Diseases in India (Summary Report 2014.08.22) 2014

MelnikowJ, HendersonJT, BurdaBU, et al. Screening for Cervical Cancer with High-

Risk Human Papillomavirus Testing: A Systematic Evidence Review for the US

Preventive Services Task Force: Evidence Synthesis No.158. Rockville, MD: Agency

for Health care Research and Quality; 2018.AHRQ publication 15-05224-EF-1.

Aswathy S, Quereshi MA, Kurian B, Leelamoni K. Cervical cancer screening: Current

knowledge and practice among women in a rural population of Kerala, India. Indian J

Med Res 2012; 136:205 10.

Screening for Cervical Cancer.US Preventive Services Task Force Recommendation

Statement. JAMA, 2018; 320(7):674-686

Nayir T, Okyay AR, Nizlican E, Yesilyurt H, Akbaba M, Ilhan B, et al. Cervical cancer

screening in an early diagnosis and screening centre in Mersin, Turkey.Asian Pac J

Cancer Prev. 2015; 16:6909-12.

Tailor HJ, Patel RD, Patel PR, Bhagat VM. Study of cervical Pap smears in a tertiary care

hospital of South Gujarat, India.Int J Res Med Sci 2016; 4:286-8.

Likhar KS, Saluja A, Gupta SG, Hazari RA, Likhar SK. Precancerous and cancerous

lesions of cervix diagnosed by Pap's smear – A hospital based study. J Evol Med and

Dent Sci 2014; 3: 1899-904.

Kaveri SB, Khandelwal S. Role of Pap smear N cervical biopsy in unhealthy cervix. J Sci

Innov Res 2015; 4:4-9.

Pradhan B, Pradhan SB, Mital VP. Correlation of Pap smear ndings with clinical

ndings and cervical biopsy. Kathmandu University Med J 2007; 5:461-7.

Shrivastava M, Shrivastava OP, Jaiswal SS. Pattern of cervical smear cytology in Rural

Medical College. Pravara Med Rev 2011; 3:4-8.

Pushp Lata Sachan, Meenakshi Singh, Munna Lal Patel, and Rekha Sachan. A Study on

Cervical Cancer Screening Using Pap Smear Test and Clinical Correlation. Asia Pac J

Oncol Nurs. 2018 Jul-Sep; 5(3): 337–341.

Bukhari MH, Saba K, Qamar S, Majeed MM, Niazi S, Naeem S. Clinicopathological

importance of Papanicolaou smears for the diagnosis of premalignant and malignant

lesions of the cervix. J Cytol 2012; 29:20-5.

Bal MS, Goyal R, Suri AK, Mohi MK. Detection of abnormal cervical cytology in

Papanicolaou smears. J Cytol 2012; 29:45-7.

Filipi K, Xhani A. Assessment of cervical cytological data in Albanian females. Asian

Pac J Cancer Prev 2014; 15:2129-32.

Atilgan R, Celik A, Boztosun A, Ilter E, Yalta T, Ozercan R, et al. Evaluation of cervical

cytological abnormalities in Turkish population. Indian J Pathol Microbiol. 2012;


Kulkarni PR, Rani H, Vimalambike MG, Ravishankar S. Opportunistic screening for

cervical cancer in a tertiary hospital in Karnataka, India. Asian Pac J Cancer Prev. 2013;


Balaha MH, Al Moghannum MS, Al Ghowinem N, Al Omran S. Cytological pattern of

cervical Papanicolaou smear in Eastern region of Saudi Arabia. J Cytol 2011;28: 173-7

Al Eyd GJ, Shaik RB. Rate of opportunistic pap smear screening and patterns of

epithelial cell abnormalities in pap smears in Ajman, United Arab Emirates. Sultan

Qaboos Univ Med J. 2012; 12:473–8.

Sarma U, Mahanta J, Talukdar K. Pattern of abnormal cervical cytology in women

attending a tertiary hospital. Int J Sci Res Publ. 2012; 2:1–4.

Bamanikar SA, Baravkar DS, Chandanwale SS, Dapkekar P. Study of cervical Pap

smears in a tertiary hospital. Ind Med Gaz 2014;148: 250-4

Padmini CP, Indira N, Chaitra R, Das P, Girish BC, Nanda KM, et al. Cytological and

colposcopic evaluation of unhealthy cervix. J Evid Med Healthc. 2015; 2:6920–7.


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